We are looking for a motivated candidate to join our next-generation T cell biology team at Juno Therapeutics. Research Associate-Exploratory Research will develop and run assessments of CAR-T cell phenotype and function. Successful candidate will have a demonstrated ability to design and execute studies to support research and development of preclinical product candidates. A range of experience in cellular T cell profiling assays, with a demonstrated ability to troubleshoot in a fast-paced dynamic environment are required. This position will have interaction with project teams and internal departments to design and execute studies to assess CAR-T cell function and persistence. Strong personal initiative, flexibility and innovative approach to problem-solving are required.

Qualifications and Education Requirements

• B.S. with > 2 years of experience in immunology research
• Solid capability with multi-parameter flow cytometry (6+ color)
• Proficiency with cellular immunology and T cell functional assays including proliferation assays, intracellular cytokine staining, and Luminex/ELISA.
• Experience with complex cell culture approaches
• Demonstrated independence in data analysis and interpretation
• Ability to work in a high paced team environment, meet deadlines, & prioritize work on multiple projects.

PREFERRED SKILLS

• Experience with cellular metabolic analysis
• Experience working with lentiviral or retroviral transduction systems
• Experience working in industry setting
• Strong verbal and written skills.

Apply at: https://www.junotherapeutics.com/working-at-juno/current-openings/?p=job%2FoCkT2fwB

Please Include a Cover letter to indicate availability for a brief face-to-face meeting at the AAI meeting.

A two-three year Postdoctoral Research Fellow Position is immediately available in the Division of Gastroenterology, Beth Israel Deaconess Medical Center / Harvard Medical School to participate in studies identifying new targets for the treatment of inflammatory bowel disease. Expertise in cell culture, cell-based immunological assays, multiplex ELISA and FACS analysis are required. Familiarity with mouse models of inflammatory or autoimmune diseases is desirable. Candidates with research experience in innate and adaptive immune responses not related to the gastrointestinal system are also encouraged to apply.

Specific requirements:
• Ph.D. , M.D. or M.D./Ph.D. in immunology, physiology, molecular and cell biology, or related disciplines
• No more than 3 years of post-doctoral training prior to the fellowship
• Must be a citizen or permanent resident (green card holder) of the US at the time of appointment.

Please email a current CV and a brief statement on your experience relevant to this position to Dr Efi Kokkotou: ekokkoto@bidmc.harvard.edu

A post-doctoral position is available immediately in the Department of Microbiology and Immunology at The University of Texas Medical Branch, Galveston, Texas, in the field of host-pathogen interactions and innate immune responses to viruses.

The lab research focuses on the regulation of innate immune signaling pathways by ubiquitin and the E3-ubiquitin ligase TRIM family of proteins, and evasion of immune responses by viruses.

For further information on the research program, visit our website: http://microbiology.utmb.edu/faculty/Rajsbaum.asp.

The potential candidates should have a Ph.D degree in one of the following fields: Biology/Life Sciences, Immunology, Virology, Molecular Biology, Cell Biology or Biochemistry.

The applicants should have a strong background in Immunology, Virology, Biochemistry and Cell Biology, and demonstrable experience using modern biochemical, cellular and molecular techniques as well as animal models. Research experience in immune signaling and ubiquitin assays is desirable but not essential.

To apply, send your curriculum vitae and a cover letter with a statement of research and technical experience by e-mail to Dr. Ricardo Rajsbaum at rirajsba@utmb.edu.

Mabtech is an accomplished biotech company developing and manufacturing products for the global market. Our customers are primarily scientists researching immune related diseases. Mabtech is a company with an excellent reputation regarding its product quality, technical expertise and exceptional service to its customers.

We are seeking a Product Specialist with responsibility for Sales and Marketing activities in the USA, Canada and some South American countries. The applicant must be outgoing and personable as you will be communicating with and meeting many researchers.

Duties –
• Member of the Sales and Marketing group of eight people
• Supply customers with product information and support on an ongoing basis
• Travel to scientific meetings and meet with researchers
• Provide current and prospective customers and the Sales and Marketing group with information and feedback about Mabtech’s products and product areas
• Proactively spread, verbally and in writing, information about Mabtech products
• Evaluate the market and find new research areas where our products can be useful tools

Customers are located throughout the Americas so Mabtech also utilizes video conferencing as a communication tool. Travel is as needed with an estimated annual total of 25-30 days per year.

https://www.mabtech.com

The Research and Development lab of the Cleveland Cord Blood Center (Cleveland, OH) is seeking a creative and motivated postdoctoral researcher to conduct regenerative medicine research. The mission of the R&D lab is to develop novel cellular based therapies using umbilical cord blood and/or technological findings supported by umbilical cord blood research. Working under the supervision of the R&D lab directors, the candidate will be involved in intellectual property design of new products, design and implementation of preclinical studies, and new product submission to the FDA for IND approval.

Principal Responsibilities
1. Independently design and perform experiments, implement protocols, analyze data, and communicate results effectively.
2. Development of assays to determine product potency, safety, stability, and storage.
3. Write and update laboratory Standard Operating Procedures (SOPs) and diligent recording of scientific data.
4. Scientific writing for peer-reviewed publications, grant submissions, and regulatory submissions.
5. Perform experiments using standard immunological and molecular methods such as cell purification and culture, qPCR, ELISA, Western blot, flow cytometry, and MLR proliferation.

Required Skills and Experience
1. A Ph.D. in immunology, molecular genetics or other related fields
2. A strong publication record
3. Excellent verbal and written communication skills

Preferred Knowledge, Skills, and Ability
1. Experience with culturing a variety of cell types and cell purification techniques
2. Flow cytometry and fluorescence microscopy
3. Previous experience with mouse models of diabetes and/or GVHD
4. Ability to work effectively as part of a team and collaborate with outside organizations
5. Good interpersonal skills

About this organization
The Cleveland Cord Blood Center (ranked 5th in the nation) collects umbilical cord blood as a source of non-controversial stem cells for use in transplants and cord blood research. The organization currently makes a product called Leucord® for hematopoietic reconstitution, and is expanding their product line to include therapies for diabetic wound healing, type I diabetes, and critical limb ischemia/peripheral artery disease. The R&D lab is ideally located on the Cleveland Clinic Campus which enhances existing collaborations with The Cleveland Clinic and Case Western Reserve University.
http://www.clevelandcordblood.org/

Contact Information
Anton Gorbachev,
Director of R&D lab of CCBC
E-mail: agorbachev@clevelandcordblood.org