Scientist/Senior Scientist Immunology, Oncology, Cell Biology

Sound Biologics
Bothell, WA

Sound Biologics is a biotechnology company focusing on the creation of innovative technology and novel therapeutics to better serve patients with cancer, inflammatory and autoimmune disease. Our purpose as a company is to discover and develop therapies that will impact human health. As we build for the future – we are looking for talented people to advance our science, produce innovative therapies and fuel our passion towards meeting unmet medical need. To meet the increasing needs of our technology and drug discovery/development efforts the Research and Development group at Sound Biologics is seeking a highly motivated Scientist/Senior Scientist with a strong background in Immunology, Oncology or preferably cancer immunotherapy and drug discovery and development to investigate and develop novel immunomodulatory therapies for cancer. In addition this individual will be part of our biological sciences team that is also investigating targeted therapies for cancer and autoimmune diseases.

The candidate will be a lead within the Biological Sciences group, as well as project teams, and will collaborate with research scientists including teams in other functional areas such as Protein engineering, cell line development and process development. The candidate will also preferably contribute more broadly to the strategic research goals and milestones of Sound Biologics drug discovery and development efforts and will be expected to publish and to present at national/international meetings.

Basic Qualifications:

• Doctorate degree & at least 2 years of scientific experience or more depending on position level, or
• Master’s degree & 6-8 years of scientific experience

Preferred Qualifications:

• Doctoral and post-doctoral training in immuno-oncology, immunology, oncology or cell biology
• Experience in a biotech setting is desirable although not required.
• Proven expertise in human and mouse immunological assays, biochemical and cell signaling approaches, imaging techniques, complex cell-based assays and relevant experimental models.
• Demonstrated track record of independent critical thinking and scientific achievement in research, exemplified by a strong publication record
• Excellent skills in written and oral communication, organization and multitasking, and working in a highly collaborative and cross-functional research environment.
• Strong verbal and written communication skills.
• Highly motivated and creative, demonstrating innovative and interdisciplinary thinking towards targeted drug discovery and the understanding of immune-mediated mechanisms in cancer.
• Advanced flow cytometry skills are required. Qualified candidate should be adept at independently designing, executing and interpreting immunology based experiments.

General Responsibilities:

The candidate will be responsible for performing the laboratory based studies to generate the nonclinical proof-of-concept datasets, enable IND submissions and identify potential PD/biomarkers to support any translational studies that may be required to facilitate product clinical development. The candidate is expected to support collaborative projects, provide experimental design expertise, conduct data analysis for in vitro and in potentially vivo studies, and provide regular research progress report(s), both written and oral, and manuscript generation as appropriate.

The responsibilities will include, but are not limited to, the following: • Lead or Work within a matrixed project team to provide preclinical rationale that supports moving lead clinical candidate for various therapeutic indications toward early development and testing of clinical hypotheses. • Explore mechanism of action, combinatorial therapeutic strategies, and elucidate translational correlates predictive of therapeutic response in Phase 1 clinical studies. • Independently design and implement long-term project plans and appropriate experiments that define efficacy and mechanism of action of the potential clinical candidate via genetic, protein and function-based in vitro assessments. Provide recommendations for, and implement studies and strategies that demonstrate the potential clinical utility through pertinent in vivo studies. • Identify and engage external experts and key opinion leaders to facilitate external assessment or collaborative opportunities to evaluate clinical candidates. • Represent the Research & Development Group in Project team/Franchise team, or other cross-functional teams as needed. • Provide scientific progress reports (or presentations) to the Director and/or Senior Management as required. • Prepare IND format documentation and / or reports based on scientific results as required. • Creates SOW and interfaces with CRO for execution of services as needed. • Provide scientific leadership to the research team, as well as, create and track achievable goals for the project team that are aligned with company goals/objectives.

Please send your C.V. and inquiry to jobs@soundbiologics.com